Stem cell treatment may offer option for broken bones that don't heal
Researchers at the University of North Carolina at Chapel Hill School of Medicine have shown in an animal study that transplantation of adult stem cells enriched with a bone-regenerating hormone can...
View ArticleScientists uncover potential target for treating common form of early-onset...
No cure exists for frontotemporal dementia, which strikes between the ages of 40 and 64 and accounts for at least one in four cases of early-onset dementia. Caused by the death of cells in the front...
View ArticleStaphylococcus aureus: Why it just gets up your nose
A collaboration between researchers at the School of Biochemistry and Immunology and the Department of Microbiology at Trinity College Dublin has identified a mechanism by which the bacterium...
View ArticleNewly identified tumor suppressor provides therapeutic target for prostate...
Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCζ suppresses prostate tumor formation. The finding, which also describes a molecular...
View ArticleResearch sheds new light on how blood clots form
Scripps Research Institute scientists have discovered new elements of the blood clot-formation process. The findings could lead to better drugs for preventing heart attacks and other clot-related...
View ArticleNarcolepsy study finds surprising increase in neurons that produce histamine
A new study provides surprising evidence that people with narcolepsy have an increased number of neurons that produce histamine, suggesting that histamine signaling may be a novel therapeutic target...
View ArticleNew study sheds light on what causes compulsive behavior, could improve OCD...
By activating a brain circuit that controls compulsive behavior, MIT neuroscientists have shown that they can block a compulsive behavior in mice—a result that could help researchers develop new...
View ArticleNew technique in RNA interference cuts time and cost in genetic screens
(Medical Xpress)—There is a new contender in the field of gene discovery, and it's giving knockout mice a run for their money. Researchers at The Rockefeller University have shown that a new technique...
View ArticleThe successful ovulation of 100 eggs from 1 female mouse
The average number of eggs for genetically modified mice (knockout mice) obtained using previous methods of superovulation induction is about 20 but in reality the number is often much smaller, about...
View ArticleStudy identifies unexpected mutation in commonly used research mice
A strain of inbred mice commonly used for the creation of so-called knockout animals has been found to carry a previously undetected mutation that could affect the results of immune system research...
View ArticleFifty-four mouse testis-enriched genes are not needed for male fertility
Infertility affects about 15 percent of couples around the world. A couple's fertility depends on both the female's and male's ability to reproduce, which relies on thousands of genes working properly....
View ArticleLoss of noncoding elements of genome results in heart abnormalities, study finds
Researchers have shown that when parts of a genome known as enhancers are missing, the heart works abnormally, a finding that bolsters the importance of DNA segments once considered "junk" because they...
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